Introduction:
Data from 2020 ESTUDES survey shows that 15,4% of Castilla y León (CyL) 14–18-year-olds had used cannabis the previous month (83.4% with tobacco). Indicated family prevention programs (IFPP) are an evidence-based effective intervention for drug consumption. These are aimed at 12-21-year-old youth with problematic use of alcohol, cannabis, or other illegal drugs. Tobacco is excluded if it is an isolated consumption but included when consumed along other drugs (such as cannabis). We refer to its use as TSDC (Tobacco as Secondary Drug Consumption). Basic goals 1. To analyze the characteristics of cases of cannabis with TSDC consumers or without TSDC among CyL IFPP users. 2. To study if there are significant differences between the two groups and between men and women.

Material and Methods:
Cases assisted by CyL IFPP from 2017 to 2021 were analyzed. The following variables from the IFPP registration form were analyzed: sex, assessment age, onset of problematic consumption age and risk factors. Qualitative variables were described using percentages. Quantitative variables were described using the mean value and the standard deviation (SD). The Chi-square test and T-student were used for evaluating the differences, p<0.05 was the reference. SPSS® Statistics 19 software was used for data analysis.

Results:
The total number of cases in IFPP was 1862 (77.6% male), with a mean age of assessment of 16.3 years (1.7 SD). 1711 cases (78.8% male) used cannabis (with other drugs or on its own). The mean age of assessment in IFPP was 16.4 years (1.6 SD) and of problematic use onset 15.0 (1.5 SD). Of these, 68.7% presented TSDC (78.1% men), while 31.3% did not use TSDC (higher proportion of men, 80.4%). TSDC consumers lived more with family (87.6% vs 83.2%;), in child protection centers (7.7% vs 5.0%) and less in judicial internment centers (1.7% vs 8.6%). Family adjustment was higher in the group with TSDC (22.9% vs 16.4%). School adjustment was better in those without TSDC (30.4% vs 36.9%). Legal problems occurred more often in that same group (29.1% vs 23.0%). All these differences were significant.

Conclusions:
- Cannabis with TSDC users have more stable housing situations and better family adjustment than those without tobacco. In TSDC school adaptation is worse. - The group of cannabis users without tobacco has a more complex profile (riskier housing situation and more legal problems) than those with TSDC.