The results of GYTS 2022 in the Czech Republic show that almost half of students (47.3 %) reported ever used tobacco. Total of 16.4 % students reported current tobacco use, currently smokes cigarettes 11.2 %. By comparison, in 2002, 34.6% of students reported currently smoking cigarettes. On the other hand, e-cigarette use has increased from 11.2% since 2016 to 21.4 % in 2022 and it is becoming more popular among the young people. Czech Republic adolescents are faced with the double burden of cigarette use and the use of other forms of tobacco products such as chewing tobacco, nicotine pouches, e-cigarettes, heated tobacco products etc. Due the aforementioned reason, the Czech Republic started policy-making processes aimed at limiting the accessibility of these products to the young population. The results are also considered in proposed interventions or further examination.